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1

ChemInform Abstract: Synthesis and Structure—Activity Relationship of Diarylamide Derivatives as Selective Inhibitors of the Proliferation of Human Coronary Artery Smooth Muscle Cells.

Haruhisa Ogita, Yoshiaki Isobe, Haruo Takaku, Rena Sekine, Yuso Goto, Satoru Misawa, Hideya Hayashi

Journal:

Année:

2001

Fichier:

PDF, 30 KB

2001

2

Synthesis and Activity of a Metabolite of (S)-6-Amino-5- (6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxamido) -3-methyl-1-phenyl-2,4-(1H,3H)-pyrimidinedione (CX-659S).

Yoshiaki Isobe, Masanori Tobe, Osamu Takahashi, Yuso Goto, Yoshifumi Inoue, Fumihiro Obara, Masami Tsuchiya, Hideya Hayashi

Journal:

Année:

2003

Fichier:

PDF, 104 KB

2003

3

Synthesis of Potent and Selective Inhibitors Against the Proliferation of Human Coronary Artery Smooth Muscle Cells.

Haruhisa Ogita, Yoshiaki Isobe, Haruo Takaku, Rena Sekine, Yuso Goto, Satoru Misawa, Hideya Hayashi

Journal:

Année:

2003

Fichier:

PDF, 98 KB

2003

4

Inhibitory Activities of Novel Pyrimidine Derivatives on the Contact Hypersensitivity Reaction.

Yoshiaki Isobe, Masanori Tobe, Yoshifumi Inoue, Yuso Goto, Fumihiro Obara, Masakazu Isobe, Hideya Hayashi

Journal:

Année:

2003

Fichier:

PDF, 110 KB

2003

5

Phorbol esters can persistently replace interleukin-2 (IL-2) for the growth of a human IL-2-dependent T-cell line

Toshikazu Takeshita, Yuso Goto, Masataka Nakamura, Masahiro Fujii, Masafumi Iwami, Yorio Hinuma, Kazuo Sugamura

Journal:

Journal of Cellular Physiology

Année:

1988

Langue:

english

Fichier:

PDF, 799 KB

english, 1988

6

Synthesis and structure–activity relationship of diarylamide derivatives as selective inhibitors of the proliferation of human coronary artery smooth muscle cells

Haruhisa Ogita, Yoshiaki Isobe, Haruo Takaku, Rena Sekine, Yuso Goto, Satoru Misawa, Hideya Hayashi

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2001

Langue:

english

Fichier:

PDF, 129 KB

english, 2001

7

Synthesis and biological evaluation of CX-659S and its related compounds for their inhibitory effects on the delayed-type hypersensitivity reaction

Masanori Tobe, Yoshiaki Isobe, Yuso Goto, Fumihiro Obara, Masami Tsuchiya, Junko Matsui, Kosaku Hirota, Hideya Hayashi

Journal:

Bioorganic & Medicinal Chemistry

Année:

2000

Langue:

english

Fichier:

PDF, 378 KB

english, 2000

8

Synthesis and structure–activity relationship of diarylamide urea derivatives as selective inhibitors of the proliferation of human coronary artery smooth muscle cells

Haruhisa Ogita, Yoshiaki Isobe, Haruo Takaku, Rena Sekine, Yuso Goto, Satoru Misawa, Hideya Hayashi

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 158 KB

english, 2002

9

Synthesis and Structure–Activity Relationship of Diarylamide Derivatives as Selective Inhibitors of the Proliferation of Human Endothelial Cells

Haruhisa Ogita, Yoshiaki Isobe, Haruo Takaku, Rena Sekine, Yuso Goto, Satoru Misawa, Hideya Hayashi

Journal:

Bioorganic & Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 784 KB

english, 2002

10

CX-659S: a novel diaminouracil derivative that has antioxidative and acute anti-inflammatory activities

Yuso Goto, Nobuo Watanabe, Noriaki Kogawa, Masami Tsuchiya, Osamu Takahashi, Hiroshi Uchi, Masutaka Furue, Hideya Hayashi

Journal:

European Journal of Pharmacology

Année:

2002

Langue:

english

Fichier:

PDF, 196 KB

english, 2002

11

Pertussis toxin inhibits differentiation induced by retinoic acid in a human promyelocytic leukemia cell line HL-60

Hiromichi Hemmi, Takehiko Nakamura, Yuso Goto, Kazuo Sugamura

Journal:

Biochemical and Biophysical Research Communications

Année:

1989

Langue:

english

Fichier:

PDF, 433 KB

english, 1989

12

Defect in prereplicative phase of G0-specific ts mutant, tsJT60

Jun Ninomiya-Tsuji, Yuso Goto, Sadahiko Ishibashi, Toshinori Ide

Journal:

Experimental Cell Research

Année:

1986

Langue:

english

Fichier:

PDF, 562 KB

english, 1986

13

Induction of cellular DNA synthesis in G0-specific ts mutant, tsJT60, following Infection with SV40 and adenoviruses

Jun Ninomiya-Tsuji, Yuso Goto, Sadahiko Ishibashi, Kazuko Shiroki, Toshinori Ide

Journal:

Experimental Cell Research

Année:

1987

Langue:

english

Fichier:

PDF, 258 KB

english, 1987

14

tsJT60, a cell cycle G0-ts mutant, becomes lethal at non-permissive temperature by transformation with adenovirus 5 when the expression of E1B gene is lacking

Yuso Goto, Jun Ninomiya-Tsuji, Kouichi Tanonaka, Sadahiko Ishibashi, Kazuko Shiroki, Toshinori Ide

Journal:

Experimental Cell Research

Année:

1987

Langue:

english

Fichier:

PDF, 2.45 MB

english, 1987

15

A cell cycle G0-ts mutant, tsJT60, becomes lethal at the nonpermissive temperature after transformation with adenovirus 12 E1B 19K mutant

Yang Yu Tai, Yuso Goto, Jun Ninomiya-Tsuji, Yumiko Kameoka, Sadahiko Ishibashi, Kazuko Shiroki, Toshinori Ide

Journal:

Experimental Cell Research

Année:

1988

Langue:

english

Fichier:

PDF, 1.13 MB

english, 1988

16

Adenosine 3′,5′-cyclic monophosphate (cAMP) inhibits phorbol ester-induced growth of an IL-2-dependent T cell line

Yuso Goto, Toshikazu Takeshita, Kazuo Sugamura

Journal:

Année:

1988

Langue:

english

Fichier:

PDF, 310 KB

english, 1988

17

Purification of an angiogenesis inhibitor from culture medium conditioned by a human chondrosarcoma-derived chondrocytic cell line, HCS-2/8

Yoichi Ohba, Yuso Goto, Yusuke Kimura, Fujio Suzuki, Tomoyuki Hisa, Kojiro Takahashi, Masaharu Takigawa

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Année:

1995

Langue:

english

Fichier:

PDF, 983 KB

english, 1995

18

ANTITHROMBOTIC EFFECTS OF NF-6505, A NOVEL ANION-BINDING EXOSITE INHIBITOR

Ryo Muramatsu, Masashi Sasaki, Nobuo Watanabe, Yuso Goto, Toru Okayama, Eriko Nukui, Tadanori Morikawa, Hideya Hayashi

Journal:

Thrombosis Research

Année:

1997

Langue:

english

Fichier:

PDF, 529 KB

english, 1997

19

Establishment of a cyclic adenosine monophosphate-dependent growing human T-cell line derived from an interleukin-2-dependent cell line

Toshikazu Takeshita, Kazuyuki Ohbo, Masataka Nakamura, Yuso Goto, Kazuo Sugamura

Journal:

Journal of Cellular Physiology

Année:

1990

Langue:

english

Fichier:

PDF, 734 KB

english, 1990

20

Inhibition of Human Telomerase by Rubromycins: Implication of Spiroketal System of the Compounds as an Active Moiety

Ueno, Takamasa, Takahashi, Hirotada, Oda, Masako, Mizunuma, Makiko, Yokoyama, Akihisa, Goto, Yuso, Mizushina, Yoshiyuki, Sakaguchi, Kengo, Hayashi, Hideya

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 200 KB

english, 2000

21

Suppressive Effect of Topically Applied CX-659S, a Novel Diaminouracil Derivative, on the Contact Hypersensitivity Reaction in Various Animal Models

Goto, Yuso, Inoue, Yoshifumi, Tsuchiya, Masami, Isobe, Masakazu, Ueno, Takamasa, Uchi, Hiroshi, Furue, Masutaka, Hayashi, Hideya

Journal:

International Archives of Allergy and Immunology

Année:

2000

Langue:

english

Fichier:

PDF, 305 KB

english, 2000

22

Synthesis and Activity of a Metabolite of (S)-6-Amino-5-(6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxamido)-3-methyl-1-phenyl-2,4-(1H,3H)-pyrimidinedione (CX-659S)

Isobe, Yoshiaki, Tobe, Masanori, Takahashi, Osamu, Goto, Yuso, Inoue, Yoshifumi, Obara, Fumihiro, Tsuchiya, Masami, Hayashi, Hideya

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Année:

2002

Langue:

english

Fichier:

PDF, 73 KB

english, 2002

23

Synthesis of Potent and Selective Inhibitors against the Proliferation of Human Coronary Artery Smooth Muscle Cells

Ogita, Haruhisa, Isobe, Yoshiaki, Takaku, Haruo, Sekine, Rena, Goto, Yuso, Misawa, Satoru, Hayashi, Hideya

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Année:

2003

Langue:

english

Fichier:

PDF, 77 KB

english, 2003

24

Inhibitory Activities of Novel Pyrimidine Derivatives on the Contact Hypersensitivity Reaction

Isobe, Yoshiaki, Tobe, Masanori, Inoue, Yoshifumi, Goto, Yuso, Obara, Fumihiro, Isobe, Masakazu, Hayashi, Hideya

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Année:

2003

Langue:

english

Fichier:

PDF, 160 KB

english, 2003

25

Pharmacological Effects of a Novel Recombinant Hirudin, CX-397, In Vivo and In Vitro: Comparison with Recombinant Hirudin Variant-1, Heparin, and Argatroban

Komatsu, Yasuhiko, Inoue, Yoshifumi, Goto, Yuso, Fukazawa, Tominaga, Hayashi, Hideya

Journal:

Thrombosis and Haemostasis

Année:

1999

Langue:

english

Fichier:

PDF, 86 KB

english, 1999